Test ID: ZG089
CPT code: 83497
Specimen Type: Plastic 24hr urine container, no preservative
Frequency: 4 – 8 days working day.
Instructions: 4 mL Urine from Plastic urine container, no preservative, Ambient. Min 1 mL aliquot.
Text: Serotonin measurement along with urinary 5-HIAA and serum chromogranin A are used in the diagnosis of carcinoid syndrome. Since most serotonin produced by carcinoid tumors is metabolized prior to reaching the circulation, the metabolic product, 5-HIAA in a 24-hour urine collection is usually the most important marker for diagnosing and monitoring treatment.
Methodology: Liquid chromatography/tandem mass spectrometry (LC/MS-MS)