Test ID: Z4434
CPT code: 84143
Specimen Type: Red, SST, or lavender top (EDTA) tube
Frequency: 5 – 10 days
Instructions: 1 mL Serum or Plasma from Red, SST, or lavender top (EDTA) tube, Frozen. Min 0.3 mL adult; 0.1 mL pediatric.
Text: 17-hydroxypregnenelone levels have been shown to remain normal in patients with Cushing. Levels can be suppressed with dexamethasone inhibition and increased with exogenous ACTH stimulation. 17-hydroxypregnenelone levels have been shown to be elevated in patients with idiopathic hirsutism.
Methodology: High-pressure liquid chromatography (HPLC) tandem mass spectrometry.