Anti-Nuclear Antibody (ANA) Fluid

• CPT Code: 86038
• LOINC:
• Specimen Type: red non-gel
• Frequency: Mon-Fri; analytic time 2 days
• Instructions: 1.0 mL Serous fluid.
• Text: The detection of antinuclear antibodies (ANA) facilitates in the diagnosis of patients with systemic autoimmune disease. Conversely, the absence of ANA in the serum of a patient with a suspected systemic autoimmune disease makes the diagnosis much less likely. The results of the ANA is reported in two parts; the titer of the antibody(s) and the pattern. The titer indicates activity and the pattern refers to distribution of staining produced by autoantibodies reacting with antigens in the Hep-2 cell nucleus, such as a homogeneous, specked, nucleolar, etc. Examples of pattern and antigen association would be a homogenous pattern due to anti-dsDNA or a speckled pattern being due to antibody to extractable nuclear antigen (ENA) such as anti-Sm or anti-RNP. COMPONENTS- Q0160 ANTINUCLEAR ANTIBODY SCREEN FLUID LOINC 14613-4; Q0161 TYPE OF FLUID LOINC 47938-6
• Methodology: Indirect Fluorescent Antibody