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Phone Icon Phone Support:  1-800-876-0243     Mail Icon  info@amsreferencelab.com     Location Icon 2916 E. Central Wichita, KS 67214    
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Test ID: ZH247

UDP-Glucuronosyl Trans 1A1-TA Genotype

  • CPT Code:
  • LOINC:
  • Specimen Type: 3mL Whole Blood REF LAV
  • Frequency: Setup Mon-Fri; analytic time: 3 days
  • Instructions: 3mLs whole blood LAV EDTA. Refrigerated. Invert several times to mix blood. Send specimen in original tube. Min. 0.4mL.
  • Text: USEFUL FOR: Identifying individuals who are at increased risk of adverse drug reactions with drugs that are metabolized by UGT1A1; especially irinotecan, but also including atazanavir, nilotinib, pazopanib, and belinostat. Identifying individuals with Gilbert syndrome due to the presence of homozygous *6, TA7, homozygous TA8, or compound heterozygous *6, TA7 or TA8. Identifying individuals who are carriers of Gilbert syndrome due to the presence of heterozygous TA7 or TA8. Components: Z7350 UGT1A1 Genotype, Z7351 UGT1A1 Phenotype, Z7352 Interpretation, Z7353 Additional Information, Z7354 Method, Z7355 Disclaimer, Z7356 Reviewed by
  • Methodology: Real-Time Polymerase Chain Reaction (PCR) with Allelic Discrimination Analysis

 

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