Acute Myeloid Leukemia (AML) FISH

• CPT Code: 88271, 88274, 88275, 88291
• LOINC:
• Specimen Type: Whole blood or Bone Marrow
• Frequency: Setup Mon-Fri; analytic time 7 days
• Instructions: 7-10mL whole blood from green Sodium Heparin tube, ambient. Min 2mL. Or 1-2mL bone marrow in sodium heparin tube. Ambient
• Text: Used for: Detecting a neoplastic clone associated with the common chromosome anomalies seen in patients with AML or other myeloid malignancies; Evaluating specimens in which standard cytogenetic analysis is unsuccessful. Detection of an abnormal clone likely indicates a diagnosis of an AML of various subtypes.
• Methodology: Fluorescence In Situ Hybridization (FISH)