ANCA

• CPT Code: 86021
• LOINC: 30538-3
• Specimen Type: SST
• Frequency: Setup: Tue, Fri; TAT 1-5 days
• Instructions: 2.0mL serum from Red or Gel tube, separate and freeze. Avoid multiple freeze/thaw cycles.
• Text: C-ANCA is present in 84-100% of patients with Generalized Wegener granulomatosis (WG). C-ANCA positive sera containing PR-3 ABS are 80% sens. and 97% specific for WG. Positive ANCA in other patients typically give a P-ANCA pattern and are usually assoc with Myeloperoxidase Abs. Components: PANCA P-ANCA; CANCA C-ANCA.
• Methodology: Microparticle multiplex immunoassay.