11-Deoxycorticosterone, Serum

Test ID: Z2830

CPT code: 82633
LOINC: 1656-8
Specimen Type: Red or Gel Clot
Frequency: Setup: Thurs; Analytic time 3-9 days
Instructions: 0.5mL serum from red. Refrigerate. SST OK.
Text: Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of 11 beta-hydroxylase 1 (CYP11B1) versus 11 beta-hydroxylase 2 (CYP11B2) deficiency, and in the diagnosis of glucocorticoid-responsive hyperaldosteronism

Evaluating congenital adrenal hyperplasia newborn screen-positive children, when elevations of 17-hydroxyprogesterone are only moderate, suggesting possible 11-hydroxylase deficiency
Methodology: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

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